TargetMol

Ilginatinib maleate

Product Code:
 
TAR-T12266L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T12266L-1mg1mg£148.00
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TAR-T12266L-2mg2mg£181.00
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TAR-T12266L-5mg5mg£258.00
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TAR-T12266L-1mL1 mL * 10 mM (in DMSO)£279.00
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TAR-T12266L-10mg10mg£332.00
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TAR-T12266L-25mg25mg£454.00
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TAR-T12266L-50mg50mg£623.00
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TAR-T12266L-100mg100mg£863.00
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TAR-T12266L-500mg500mg£1,661.00
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This product comes from: United States.
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Further Information

Bioactivity:
Ilginatinib maleate is a highly active and orally bioavailable inhibitor of JAK2.
CAS:
1354799-87-3
Formula:
C25H24FN7O4
Molecular Weight:
505.51
Pathway:
Chromatin/Epigenetic; Stem Cells; Tyrosine Kinase/Adaptors; JAK/STAT signaling; Angiogenesis
Purity:
0.9968
SMILES:
OC(=O)C=C/C(O)=O.C[C@H](Nc1cc(cc(Nc2cnccn2)n1)-c1cnn(C)c1)c1ccc(F)cc1
Target:
Tyrosine Kinases; JAK

References

1. Nakaya Y, et al. Efficacy of NS-018, a potent and selective JAK2/Src inhibitor, in primary cells and mouse models of myeloproliferative neoplasms. Blood Cancer J. 2011 Jul;1(7):e29. 2. Kuroda J, et al. NS-018, a selective JAK2 inhibitor, preferentially inhibits CFU-GM colony formation by bone marrow mononuclear cells from high-risk myelodysplastic syndrome patients. Leuk Res. 2014 May;38(5):619-24.