TargetMol

BAY-85-8501

Product Code:
 
TAR-T12613L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12613L-1mg1mg£214.00
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Quantity:
TAR-T12613L-5mg5mg£436.00
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Quantity:
TAR-T12613L-1mL1 mL * 10 mM (in DMSO)£464.00
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TAR-T12613L-10mg10mg£610.00
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Quantity:
TAR-T12613L-25mg25mg£922.00
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Quantity:
TAR-T12613L-50mg50mg£1,219.00
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Quantity:
TAR-T12613L-100mg100mg£1,613.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BAY-85-8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE; IC50 of 65 pM)
CAS:
1161921-82-9
Formula:
C22H17F3N4O3S
Molecular Weight:
474.46
Pathway:
Proteases/Proteasome
Purity:
0.9863
SMILES:
CN1[C@@H](C(C#N)=C(C)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1S(C)(=O)=O)C#N
Target:
Serine Protease

References

1. Von Nussbaum F, et al. Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases. ChemMedChem. 2015 Jul;10(7):1163-73.