TargetMol

(Rac)-MGV354

Product Code:
 
TAR-T12670
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12670-1mg1mg£127.00
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TAR-T12670-5mg5mg£209.00
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TAR-T12670-1mL1 mL * 10 mM (in DMSO)£250.00
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TAR-T12670-10mg10mg£294.00
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TAR-T12670-25mg25mg£523.00
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TAR-T12670-50mg50mg£707.00
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Quantity:
TAR-T12670-100mg100mg£978.00
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This product comes from: United States.
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Further Information

Bioactivity:
(Rac)-MGV354 is the racemate of MGV354. MGV354 is a soluble activator of guanylate cyclase (sGC)(EC50s of <0.5 nM, and 5 nM in CHO and GTM-3 E cells, respectively).
CAS:
1852495-86-3
Formula:
C35H37N5O3
Molecular Weight:
575.713
Purity:
0.9875
SMILES:
Cc1c(cnn1-c1cccc(n1)-c1cccc2CCC(Nc3ccc(cc3C)C3CCN(CC3)C(=O)C3CC3)c12)C(O)=O

References

1. Ehara T, et al. The Discovery of ( S)-1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1 H-inden-4-yl)pyridin-2-yl)-5-methyl-1 H-pyrazole-4-carboxylic Acid, a Soluble Guanylate Cyclase Activator Specifically Designed for Topical Ocular Delivery as a Therapy for Glaucoma. J Med Chem. 2018 Mar 22;61(6):2552-2570.