TargetMol

SAR7334

Product Code:
 
TAR-T12849
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12849-1mg1mg£123.00
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TAR-T12849-5mg5mg£201.00
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TAR-T12849-1mL1 mL * 10 mM (in DMSO)£213.00
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TAR-T12849-10mg10mg£282.00
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TAR-T12849-25mg25mg£412.00
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TAR-T12849-50mg50mg£550.00
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TAR-T12849-100mg100mg£670.00
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Further Information

Bioactivity:
SAR7334 is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).
CAS:
1333210-07-3
Formula:
C21H22ClN3O
Molecular Weight:
367.87
Pathway:
Membrane transporter/Ion channel
Purity:
0.9962
SMILES:
N[C@H](CCC1)CN1[C@H](Cc1c2cccc1)[C@@H]2Oc(ccc(C#N)c1)c1Cl
Target:
TRP/TRPV Channel

References

1. Ilatovskaya DV, et al. The Role of Angiotensin II in Glomerular Volume Dynamics and Podocyte Calcium Handling. Sci Rep. 2017 Mar 22;7(1):299. 2. Chauvet S, et al. Pharmacological Characterization of the Native Store-Operated Calcium Channels of Cortical Neurons from Embryonic Mouse Brain. Front Pharmacol. 2016 Dec 12;7:486. 3. Maier T, et al. Discovery and pharmacological characterization of a novel potent inhibitor of diacylglycerol-sensitive TRPC cation channels. Br J Pharmacol. 2015 Jul;172(14):3650-60.