TargetMol

SIBA

Product Code:
 
TAR-T12908
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12908-1mg1mg£130.00
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TAR-T12908-5mg5mg£198.00
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TAR-T12908-1mL1 mL * 10 mM (in DMSO)£212.00
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TAR-T12908-10mg10mg£230.00
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TAR-T12908-25mg25mg£380.00
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TAR-T12908-50mg50mg£533.00
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Quantity:
TAR-T12908-100mg100mg£732.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
SIBA is a synthetic analogue of SAH, acts as an inhibitor of S-adenosylmethionine-mediated transmethylation. SIBA can interfere with a variety of enzymatic activities in vitro, such as SAH hydrolase, methylthioadenosine phosphorylase and cAMP phosphodiesterase. SIBA reversibly blocks the multiplication of herpes simplex type 1 virus (HSV)
CAS:
35899-54-8
Formula:
C14H21N5O3S
Molecular Weight:
339.41
Pathway:
DNA Damage/DNA Repair; Microbiology/Virology; Cell Cycle/Checkpoint
Purity:
0.9915
SMILES:
CC(C)CSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Target:
Nucleoside Antimetabolite/Analog; HSV

References

1. Carteni-Farina M, et al. Studies on the metabolism of 5'-isobutylthioadenosine (SIBA): phosphorolytic cleavage by methylthioadenosinephosphorylase. FEBS Lett. 1979 Aug 15;104(2):266-270. 2. Lawrence F, et al. Effect of 5'-deoxy-5'-isobutylthioadenosine on putrescine uptake and polyamine biosynthesis by chick embryofibroblasts. Biochem J. 1982 Jun 15;204(3):853-859.