TargetMol

SID 26681509

Product Code:
 
TAR-T12909
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12909-1mg1mg£119.00
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TAR-T12909-5mg5mg£189.00
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TAR-T12909-1mL1 mL * 10 mM (in DMSO)£211.00
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TAR-T12909-10mg10mg£254.00
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TAR-T12909-25mg25mg£439.00
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TAR-T12909-50mg50mg£622.00
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Quantity:
TAR-T12909-100mg100mg£857.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).
CAS:
958772-66-2
Formula:
C27H33N5O5S
Molecular Weight:
539.65
Pathway:
Proteases/Proteasome; Microbiology/Virology
Purity:
0.98
SMILES:
CCc1ccccc1NC(=O)CSC(=O)NNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Target:
Cysteine Protease; Parasite

References

1. Shah PP, et al. Kinetic characterization and molecular docking of a novel, potent, and selective slow-binding inhibitor of human cathepsin L. Mol Pharmacol. 2008 Jul;74(1):34-41. 2. Pribis JP, et al. The HIV Protease Inhibitor Saquinavir Inhibits HMGB1-Driven Inflammation by Targeting the Interaction of Cathepsin V with TLR4/MyD88. Mol Med. 2015 Dec;21(1):749-757.