TargetMol

SIRT-IN-1

Product Code:
 
TAR-T12918
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12918-1mg1mg£138.00
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TAR-T12918-5mg5mg£229.00
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TAR-T12918-1mL1 mL * 10 mM (in DMSO)£284.00
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TAR-T12918-10mg10mg£334.00
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TAR-T12918-25mg25mg£519.00
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TAR-T12918-50mg50mg£703.00
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TAR-T12918-100mg100mg£970.00
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TAR-T12918-500mg500mg£1,862.00
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This product comes from: United States.
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Further Information

Bioactivity:
SIRT-IN-1 is a potent SIRT1/2/3 inhibitor(IC50s of 15, 10, 33 μM, respectively).
CAS:
1431411-60-7
Formula:
C19H27N5O2S
Molecular Weight:
389.52
Pathway:
Chromatin/Epigenetic; DNA Damage/DNA Repair
Purity:
0.98
SMILES:
CC(C)(C)C(=O)NCCC1CCN(CC1)c1ncnc2cc(sc12)C(N)=O
Target:
Sirtuin

References

1. Disch JS, et al. Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3. J Med Chem. 2013 May 9;56(9):3666-79.