TargetMol

SN50 acetate (213546-53-3 free base)

Product Code:
 
TAR-T12942L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T12942L-1mg1mg£136.00
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TAR-T12942L-5mg5mg£333.00
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TAR-T12942L-10mg10mg£466.00
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TAR-T12942L-25mg25mg£703.00
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TAR-T12942L-50mg50mg£970.00
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Quantity:
TAR-T12942L-100mg100mg£1,267.00
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Further Information

Bioactivity:
SN50 acetate is a cell permeable inhibitor of NF-κB translocation.
CAS:
T12942L
Formula:
C131H234N36O31S
Molecular Weight:
2841.55
Pathway:
NF-κb
Purity:
0.9986
SMILES:
O=C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N1[C@@H](CCC1)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N2[C@@H](CCC2)C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CCSC)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N.CC(O)=O
Target:
NF-κB

References

1. Sun Y X , Dai D K , Liu R , et al. Therapeutic effect of SN50, an inhibitor of nuclear factor-?B, in treatment of TBI in mice[J]. Neurological Sciences, 2013, 34(3):345-355. 2. Szymura S . Therapeutic Effect of Topical Administration of SN50, an Inhibitor of Nuclear Factor-?B, in Treatment of Corneal Alkali Burns in Mice[J]. American Journal of Pathology, 2005, 166(3):1393-1403. 3. Zhao K , Zhu B S , Gong W , et al. SN50 enhances the effects of LY294002 on cell death induction in gastric cancer cell line SGC7901[J]. Archives of Medical Science Ams, 2013, 9:990-998. 4. Chian C F , Chiang C H , Chuang C H , et al. Inhibitor of nuclear factor-?B, SN50, attenuates lipopolysaccharide-induced lung injury in an isolated and perfused rat lung model[J]. Translational Research, 2014, 163(3):211-220.