TargetMol

SynuClean-D

Product Code:
 
TAR-T13048
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T13048-1mg1mg£213.00
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TAR-T13048-5mg5mg£371.00
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TAR-T13048-1mL1 mL * 10 mM (in DMSO)£401.00
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TAR-T13048-10mg10mg£550.00
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TAR-T13048-25mg25mg£845.00
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TAR-T13048-50mg50mg£1,107.00
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Quantity:
TAR-T13048-100mg100mg£1,484.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
SynuClean-D is an α-synuclein aggregation inhibitor preventing fibril propagation, disrupting mature amyloid fibrils, and abolishing the degeneration of dopaminergic neurons in an animal model of Parkinson?s disease.
CAS:
685121-45-3
Formula:
C13H5F3N4O5
Molecular Weight:
354.201
Purity:
0.9925
SMILES:
Oc1nc(-c2cccc(c2)[N+]([O-])=O)c(c(c1C#N)C(F)(F)F)[N+]([O-])=O

References

1. Pujols J, et al. Small molecule inhibits ?-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10481-10486.