TargetMol

YQ128

Product Code:
 
TAR-T13375
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13375-1mg1mg£111.00
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TAR-T13375-5mg5mg£168.00
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TAR-T13375-1mL1 mL * 10 mM (in DMSO)£189.00
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TAR-T13375-10mg10mg£229.00
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TAR-T13375-25mg25mg£329.00
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TAR-T13375-50mg50mg£503.00
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TAR-T13375-100mg100mg£695.00
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This product comes from: United States.
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Further Information

Bioactivity:
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 ?M), with anti-inflammatory activity.
CAS:
2454246-18-3
Formula:
C27H29ClN2O4S2
Molecular Weight:
545.11
Pathway:
NF-κb; Immunology/Inflammation
Purity:
0.98
SMILES:
CCCOc1ccc(Cl)cc1CN(CCc1ccc(cc1)S(=O)(=O)NCC#C)C(=O)Cc1ccsc1
Target:
IL Receptor; NOD-like Receptor (NLR); NOD; Interleukin

References

1. 1.Jiang Y, et al. Discovery of Second-Generation NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization. J Med Chem. 2019 Oct 31.