TargetMol

ZM223

Product Code:
 
TAR-T13412
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13412-1mg1mg£227.00
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Quantity:
TAR-T13412-2mg2mg£306.00
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Quantity:
TAR-T13412-5mg5mg£430.00
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TAR-T13412-10mg10mg£599.00
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TAR-T13412-25mg25mg£863.00
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Quantity:
TAR-T13412-50mg50mg£1,179.00
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Quantity:
TAR-T13412-100mg100mg£1,589.00
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Quantity:
TAR-T13412-500mg500mg£3,107.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ZM223 is an inhibitor of NEDD8 activating enzyme (NAE).
CAS:
2031177-48-5
Formula:
C23H17F3N4O2S2
Molecular Weight:
502.53
Pathway:
Ubiquitination
Purity:
0.9967
SMILES:
O=C(NC1=NC=2C=CC(=CC2S1)NC(=O)CSC3=CC=C(N)C=C3)C4=CC=C(C=C4)C(F)(F)F
Target:
E1/E2/E3 Enzyme

References

1. Ma H, et al. Discovery of benzothiazole derivatives as novel non-sulfamide NEDD8 activating enzyme inhibitors by target-based virtual screening. Eur J Med Chem. 2017 Jun 16;133:174-183.