TargetMol

BMVC-8C3O

Product Code:
 
TAR-T13584
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13584-1mg1mg£215.00
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TAR-T13584-2mg2mg£273.00
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TAR-T13584-5mg5mg£356.00
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TAR-T13584-10mg10mg£495.00
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TAR-T13584-1mL1 mL * 10 mM (in DMSO)£624.00
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TAR-T13584-25mg25mg£757.00
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TAR-T13584-50mg50mg£1,018.00
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TAR-T13584-100mg100mg£1,348.00
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This product comes from: United States.
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Further Information

Bioactivity:
BMVC-8C3O is a DNA G-quadruplexe (G4) ligand, can induce topological conversion of non-parallel to parallel forms in human telomeric DNA G4s.
CAS:
1301708-12-2
Formula:
C42H53I3N4O3
Molecular Weight:
1042.624
Pathway:
DNA Damage/DNA Repair; Cell Cycle/Checkpoint
Purity:
0.9972
SMILES:
[I-].[I-].[I-].C[n+]1ccc(C=Cc2ccc3n(CCOCCOCCOCC[N+]4(C)CCCCC4)c4ccc(C=Cc5cc[n+](C)cc5)cc4c3c2)cc1
Target:
DNA/RNA Synthesis

References

1. Wang ZF, et al. A novel transition pathway of ligand-induced topological conversion from hybrid forms to parallel forms of human telomeric G-quadruplexes. Nucleic Acids Res. 2016 May 5;44(8):3958-68. 2. Wang ZF, Chang TC. Molecular engineering of G-quadruplex ligands based on solvent effect of polyethylene glycol. Nucleic Acids Res. 2012 Sep 1;40(17):8711-20.