TargetMol

Ch55

Product Code:
 
TAR-T14946
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14946-1mg1mg£103.00
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TAR-T14946-5mg5mg£148.00
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TAR-T14946-1mL1 mL * 10 mM (in DMSO)£156.00
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TAR-T14946-10mg10mg£189.00
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TAR-T14946-25mg25mg£300.00
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TAR-T14946-50mg50mg£490.00
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TAR-T14946-100mg100mg£680.00
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TAR-T14946-500mg500mg£1,340.00
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Further Information

Bioactivity:
Ch55 is an effective inducer of the differentiation of HL60 cells (EC50 = 200 nM) and shows high affinity with RAR-α and RAR-β receptors. Ch55 can be used in studies about cancer.
CAS:
110368-33-7
Formula:
C24H28O3
Molecular Weight:
364.48
Pathway:
Metabolism
Purity:
0.98
SMILES:
CC(C)(C)c1cc(cc(c1)C(C)(C)C)C(=O)C=Cc1ccc(cc1)C(O)=O
Target:
Retinoid Receptor

References

1. Jetten AM, et al. New benzoic acid derivatives with retinoid activity: lack of direct correlation between biological activity and binding to cellular retinoic acid binding protein. Cancer Res. 1987 Jul 1;47(13):3523-7. 2. Takahashi N, et al. Induction of differentiation and covalent binding to proteins by the synthetic retinoids Ch55 and Am80. Arch Biochem Biophys. 1994 Oct;314(1):82-9.