TargetMol

Chroman 1

Product Code:
 
TAR-T14960
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14960-1mg1mg£127.00
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TAR-T14960-5mg5mg£209.00
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TAR-T14960-1mL1 mL * 10 mM (in DMSO)£226.00
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TAR-T14960-10mg10mg£294.00
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TAR-T14960-25mg25mg£481.00
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TAR-T14960-50mg50mg£666.00
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TAR-T14960-100mg100mg£863.00
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Further Information

Bioactivity:
Chroman 1 is a potent inhibitor of ROCK1 (IC50?= 52 pM) and ROCK2 (IC50?= 1 pM).
CAS:
1273579-40-0
Formula:
C24H28N4O4
Molecular Weight:
436.512
Pathway:
Cell Cycle/Checkpoint; Stem Cells; Cytoskeletal Signaling
Purity:
0.9991
SMILES:
COc1ccc2OC[C@H](Cc2c1)C(=O)Nc1ccc(cc1OCCN(C)C)-c1cn[nH]c1
Target:
ROCK

References

1. Yen Ting Chen, et al. Asymmetric synthesis of potent chroman-based Rho kinase (ROCK-II) inhibitors. Med.Chem.Commun., 2011, 2, 73-75.