TargetMol

EF-5

Product Code:
 
TAR-T15202
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15202-1mg1mg£95.00
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TAR-T15202-5mg5mg£128.00
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TAR-T15202-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T15202-10mg10mg£168.00
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TAR-T15202-25mg25mg£269.00
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TAR-T15202-50mg50mg£389.00
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TAR-T15202-100mg100mg£544.00
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Further Information

Bioactivity:
EF-5 is a agent of hypoxia labeling. It is used to identify hypoxia in cells.
CAS:
152721-37-4
Formula:
C8H7F5N4O3
Molecular Weight:
302.161
Purity:
0.9826
SMILES:
[O-][N+](=O)c1nccn1CC(=O)NCC(F)(F)C(F)(F)F

References

1. Wang J, et al. The 2-nitroimidazole EF5 is a biomarker for oxidoreductases that activate the bioreductive prodrug CEN-209 under hypoxia. Clin Cancer Res. 2012 Mar 15;18(6):1684-95. 2. Evans SM, et al. Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]. Br J Cancer. 1995 Oct;72(4):875-82.