TargetMol

FMK 9a

Product Code:
 
TAR-T15303
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15303-1mg1mg£185.00
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TAR-T15303-5mg5mg£351.00
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TAR-T15303-1mL1 mL * 10 mM (in DMSO)£359.00
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TAR-T15303-10mg10mg£487.00
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TAR-T15303-25mg25mg£747.00
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TAR-T15303-50mg50mg£1,002.00
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TAR-T15303-100mg100mg£1,332.00
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TAR-T15303-500mg500mg£2,585.00
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This product comes from: United States.
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Further Information

Bioactivity:
FMK 9a is an irreversible inhibitor of ATG4B with IC50 values of 80 and 73 nM in the TR-FRET and cellular-based LRA assays.
CAS:
1955550-51-2
Formula:
C23H21FN2O3
Molecular Weight:
392.43
Pathway:
Proteases/Proteasome; Autophagy
Purity:
0.98
SMILES:
FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc2ccccc12
Target:
Cysteine Protease; Autophagy

References

1. Qiu Z, et al. Discovery of Fluoromethylketone-Based Peptidomimetics as Covalent ATG4B (Autophagin-1) Inhibitors. ACS Med Chem Lett. 2016 Jun 25;7(8):802-6.