TargetMol

Fumitremorgin C

Product Code:
 
TAR-T15355
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15355-1mg1mg£261.00
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Further Information

Bioactivity:
Fumitremorgin C is a mycotoxin and inhibits ABCG2/BRCP.
CAS:
118974-02-0
Formula:
C22H25N3O3
Molecular Weight:
379.46
Pathway:
Membrane transporter/Ion channel; Microbiology/Virology
Purity:
0.98
SMILES:
[H][C@@]12CCCN1C(=O)[C@]1([H])Cc3c([nH]c4cc(OC)ccc34)[C@]([H])(C=C(C)C)N1C2=O
Target:
BCRP; Antibacterial; Antibiotic; ABC

References

1. Rabindran SK, et al. Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C. Cancer Res. 1998 Dec 15;58(24):5850-8. 2. Rabindran SK, et al. Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res. 2000 Jan 1;60(1):47-50.