TargetMol

G-1

Product Code:
 
TAR-T15364
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15364-1mg1mg£105.00
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Quantity:
TAR-T15364-1mL1 mL * 10 mM (in DMSO)£131.00
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Quantity:
TAR-T15364-5mg5mg£135.00
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TAR-T15364-10mg10mg£172.00
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Quantity:
TAR-T15364-25mg25mg£250.00
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Quantity:
TAR-T15364-50mg50mg£367.00
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Quantity:
TAR-T15364-100mg100mg£497.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
G-1 is a nonsteroidal, high-affinity and selective GPR30 agonist (Ki: 11 nM).
CAS:
881639-98-1
Formula:
C21H18BrNO3
Molecular Weight:
412.283
Pathway:
GPCR/G Protein; Endocrinology/Hormones
Purity:
0.9814
SMILES:
[H][C@@]12CC=C[C@]1([H])c1cc(ccc1N[C@@H]2c1cc2OCOc2cc1Br)C(C)=O
Target:
Estrogen Receptor/ERR; GPR

References

1. Cheng Q, et al. G-1 exerts neuroprotective effects through G protein-coupled estrogen receptor 1 following spinal cord injury in mice. Biosci Rep. 2016 Aug 31;36(4). pii: e00373. 2. Kurt AH, et al. Oxidative/antioxidative enzyme-mediated antiproliferative and proapoptotic effects of the GPER1 agonist G-1 on lung cancer cells. Oncol Lett. 2015 Nov;10(5):3177-3182. 3. Chimento A, et al. GPER agonist G-1 decreases adrenocortical carcinoma (ACC) cell growth in vitro and in vivo. Oncotarget. 2015 Aug 7;6(22):19190-203.