TargetMol

Incyclinide

Product Code:
 
TAR-T15574
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15574-1mg1mg£135.00
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Quantity:
TAR-T15574-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T15574-5mg5mg£168.00
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TAR-T15574-10mg10mg£230.00
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TAR-T15574-25mg25mg£413.00
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TAR-T15574-50mg50mg£591.00
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Quantity:
TAR-T15574-100mg100mg£812.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Incyclinide is a matrix metalloproteinase (MMP) inhibitor. Thereby causing extracellular matrix degradation, tumor growth and invasion, and inhibiting angiogenesis, and metastasis.
CAS:
15866-90-7
Formula:
C19H17NO7
Molecular Weight:
371.345
Pathway:
Proteases/Proteasome
Purity:
0.9781
SMILES:
[H][C@@]12Cc3cccc(O)c3C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)C[C@]1([H])C2
Target:
MMP

References

1. Lee HM, et al. CMT-3, a non-antimicrobial tetracycline (TC), inhibits MT1-MMPactivity: relevance to cancer. Curr Med Chem. 2001 Feb;8(3):257-60. 2. Liu Y, A chemically modified tetracycline (CMT-3) is a new antifungal agent. Antimicrob Agents Chemother. 2002 May;46(5):1447-54. 3. Bildt MM, et al. CMT-3 inhibits orthodontic tooth displacement in the rat. Arch Oral Biol. 2007 Jun;52(6):571-8.