TargetMol

IU1-47

Product Code:
 
TAR-T15604
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15604-1mg1mg£111.00
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TAR-T15604-2mg2mg£130.00
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TAR-T15604-5mg5mg£168.00
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TAR-T15604-1mL1 mL * 10 mM (in DMSO)£177.00
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TAR-T15604-10mg10mg£222.00
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TAR-T15604-25mg25mg£382.00
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TAR-T15604-50mg50mg£534.00
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TAR-T15604-100mg100mg£734.00
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Quantity:
TAR-T15604-500mg500mg£1,420.00
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This product comes from: United States.
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Further Information

Bioactivity:
IU1-47 is an effective and specific USP14 inhibitor (IC50: 0.6 μM). IU1-47 causes tau elimination in cultured neurons. IU1-47 inhibits IsoT/USP5 (IC50: 20 μM).
CAS:
670270-31-2
Formula:
C19H23ClN2O
Molecular Weight:
330.86
Pathway:
Ubiquitination; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Purity:
0.9955
SMILES:
Cc1cc(C(=O)CN2CCCCC2)c(C)n1-c1ccc(Cl)cc1
Target:
DUB

References

1. Boselli M, et al. An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons. J Biol Chem. 2017 Nov 24;292(47):19209-19225.