TargetMol

KDM5-IN-1

Product Code:
 
TAR-T15649
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15649-1mg1mg£149.00
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Quantity:
TAR-T15649-1mL1 mL * 10 mM (in DMSO)£258.00
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Quantity:
TAR-T15649-5mg5mg£333.00
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Quantity:
TAR-T15649-10mg10mg£470.00
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Quantity:
TAR-T15649-25mg25mg£707.00
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Quantity:
TAR-T15649-50mg50mg£978.00
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Quantity:
TAR-T15649-100mg100mg£1,291.00
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Quantity:
TAR-T15649-500mg500mg£2,456.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
KDM5-IN-1 is an effective and selective inhibitor of KDM5 with an IC50 of 15.1 nM.
CAS:
1628210-26-3
Formula:
C17H20N6O
Molecular Weight:
324.388
Pathway:
Chromatin/Epigenetic
Purity:
0.98
SMILES:
CC(C)c1c([nH]c2c(cnn2c1=O)C#N)-c1cnn(c1)C(C)(C)C
Target:
Histone Demethylase

References

1. Liang J, et al. Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studies. Bioorg Med Chem Lett. 2016 Aug 15;26(16):4036-41.