TargetMol

L-689560

Product Code:
 
TAR-T15684
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15684-1mg1mg£265.00
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TAR-T15684-5mg5mg£470.00
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TAR-T15684-10mg10mg£686.00
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TAR-T15684-25mg25mg£1,123.00
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Quantity:
TAR-T15684-50mg50mg£1,661.00
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Further Information

Bioactivity:
L-689560 is widely used as a radiolabeled ligand in binding studies and used to study the roles of NMDA receptors in normal neurological processes as well as in diseases. At the GluN1 glycine binding site, L-689560 is an effective N-methyl-D-aspartate (NMDA) receptor antagonist.
CAS:
139051-78-8
Formula:
C17H15Cl2N3O3
Molecular Weight:
380.23
Pathway:
Neuroscience; Membrane transporter/Ion channel
Purity:
0.98
SMILES:
OC(=O)[C@H]1C[C@H](NC(=O)Nc2ccccc2)c2c(Cl)cc(Cl)cc2N1
Target:
NMDAR; iGluR

References

1. Juan Chen, et al. A non-ionotropic activity of NMDA receptors contributes to glycine-induced neuroprotection in cerebral ischemia-reperfusion injury. 15 June 2017 2. Kvist T, et al. Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. J Biol Chem. 2013 Nov 15;288(46):33124-35.