TargetMol

Latrunculin A

Product Code:
 
TAR-T15721
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15721-1mg1mg£1,964.00
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Further Information

Bioactivity:
Latrunculin A is a toxin isolated from the red sea sponge Latrunculia magnifica. Latrunculin A binds to actin monomers and it also inhibits polymerization of actin (Kds: 0.1, 0.4, 4.7 μM, and 0.19 μM for ATP-actin, ADP-Pi-actin, ADP-actin, and G-actin, respectively).
CAS:
76343-93-6
Formula:
C22H31NO5S
Molecular Weight:
421.55
Purity:
0.98
SMILES:
[H][C@@]12C[C@]([H])(C[C@@](O)(O1)[C@@H]1CSC(=O)N1)OC(=O)C=C(C)/CCC=CC=C/[C@@H](C)CC2

References

1. Fujiwara I, et al. Latrunculin A Accelerates Actin Filament Depolymerization in Addition to Sequestering Actin Monomers. Curr Biol. 2018 Oct 8;28(19):3183-3192.e2. 2. Cou? M, et al. Inhibition of actin polymerization by latrunculin A. FEBS Lett. 1987 Mar 23;213(2):316-8.