TargetMol

Limaprost

Product Code:
 
TAR-T15757
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15757-1mg1mg£132.00
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TAR-T15757-1mL1 mL * 10 mM (in DMSO)£218.00
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TAR-T15757-5mg5mg£235.00
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TAR-T15757-10mg10mg£373.00
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TAR-T15757-25mg25mg£789.00
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TAR-T15757-50mg50mg£1,383.00
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Further Information

Bioactivity:
Limaprost is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost can be used for pain relief, has antianginal effects, and has potential for ischaemic symptoms treatment.
CAS:
74397-12-9
Formula:
C22H36O5
Molecular Weight:
380.525
Pathway:
Immunology/Inflammation
Purity:
0.9989
SMILES:
CCCC[C@H](C)C[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCC=CC(O)=O
Target:
PGE Synthase

References

1. Tsuboi T, et al. Pharmacological evaluation of OP 1206, a prostaglandin E1 derivative, as an antianginal agent. Arch Int Pharmacodyn Ther. 1980 Sep;247(1):89-102. 2. Swainston Harrison T, et al. Limaprost. Drugs. 2007;67(1):109-18; discussion 119-20. 3. Murata K, et al. PGE1 Attenuates IL-1?-induced NGF Expression in Human Intervertebral Disc Cells. Spine (Phila Pa 1976). 2016 Jun;41(12):E710-6.