TargetMol

Lobaplatin

Product Code:
 
TAR-T15771
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T15771-50mg50mgEnquire
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TAR-T15771-25mg25mg£675.00
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Further Information

Bioactivity:
Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin (D-19466) is a third-generation platinum anti-neoplastic agent which shows activity for a variety of tumour types and is a promising antitumour chemotherapeutic agent[1][2]. It is a platinum complex with DNA alkylating activity.
CAS:
135558-11-1
Formula:
C9H14N2O3Pt
Molecular Weight:
393.306
Pathway:
DNA Damage/DNA Repair
Purity:
0.98
SMILES:
CC1[O-][Pt++]2([N]CC3CCC3C[N]2)[O-]C1=O
Target:
DNA Alkylation

References

1. Cao H, et al. Lobaplatin Inhibits Prostate Cancer Proliferation and Migration Through Regulation of BCL2 and BAX. Dose Response. 2019 Jun 5;17(2):1559325819850981. 2. McKeage MJ, et al. Lobaplatin: a new antitumour platinum drug. Expert Opin Investig Drugs. 2001 Jan;10(1):119-28.