TargetMol

MI-538

Product Code:
 
TAR-T16072
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16072-1mg1mg£148.00
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TAR-T16072-5mg5mg£261.00
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TAR-T16072-1mL1 mL * 10 mM (in DMSO)£308.00
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TAR-T16072-10mg10mg£405.00
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TAR-T16072-25mg25mg£630.00
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TAR-T16072-50mg50mg£867.00
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Quantity:
TAR-T16072-100mg100mg£1,139.00
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Further Information

Bioactivity:
MI-538 is an interaction between menin and MLL fusion proteins inhibitor(IC50 of 21 nM).
CAS:
1857417-10-7
Formula:
C27H25F3N8OS
Molecular Weight:
566.61
Pathway:
Chromatin/Epigenetic
Purity:
0.9931
SMILES:
Oc1cc2n(Cc3cn[nH]c3)c(cc2cc1CN1CCC(CC1)Nc1ncnc2sc(CC(F)(F)F)cc12)C#N
Target:
Epigenetic Reader Domain; Histone Methyltransferase

References

1. Borkin D, et al. Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein-Protein Interaction between Menin and Mixed Lineage Leukemia (MLL). J Med Chem. 2016 Feb 11;59(3):892-913.