TargetMol

MK-0812 Succinate

Product Code:
 
TAR-T16091
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16091-50mg50mgEnquire
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TAR-T16091-1mg1mg£118.00
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TAR-T16091-2mg2mg£139.00
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TAR-T16091-5mg5mg£189.00
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TAR-T16091-1mL1 mL * 10 mM (in DMSO)£222.00
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TAR-T16091-10mg10mg£293.00
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TAR-T16091-25mg25mg£522.00
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This product comes from: United States.
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Further Information

Bioactivity:
MK-0812 Succinate is an effective and selective CCR2 antagonist.
CAS:
851916-42-2
Formula:
C28H40F3N3O7
Molecular Weight:
587.637
Pathway:
; Microbiology/Virology; Immunology/Inflammation
Purity:
0.9862
SMILES:
OC(=O)CCC(O)=O.CO[C@@H]1COCC[C@@H]1N[C@@H]1CC[C@](C1)(C(C)C)C(=O)N1CCc2ncc(cc2C1)C(F)(F)F
Target:
CCR

References

1. Min SH, et al. Pharmacological targeting reveals distinct roles for CXCR2/CXCR1 and CCR2 in a mouse model of arthritis.Biochem Biophys Res Commun. 2010 Jan 1;391(1):1080-6. 2. Wisniewski T, et al. Assessment of chemokine receptor function on monocytes in whole blood: In vitro and ex vivo evaluations of a CCR2 antagonist.J Immunol Methods. 2010 Jan 31;352(1-2):101-10.