TargetMol

ML604086

Product Code:
 
TAR-T16111
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16111-1mg1mg£132.00
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TAR-T16111-2mg2mg£157.00
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TAR-T16111-5mg5mg£201.00
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TAR-T16111-1mL1 mL * 10 mM (in DMSO)£217.00
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TAR-T16111-10mg10mg£302.00
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TAR-T16111-25mg25mg£460.00
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Quantity:
TAR-T16111-50mg50mg£627.00
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This product comes from: United States.
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Further Information

Bioactivity:
ML604086 suppresses CCL1 mediated chemotaxis and enhances intracellular Ca2 concentrations. ML604086 is a selective inhibitor of CCR8. It also inhibiting CCL1 binding to CCR8 on circulating T-cells.
CAS:
850330-18-6
Formula:
C27H32N4O4S
Molecular Weight:
508.64
Pathway:
Immunology/Inflammation; Microbiology/Virology
Purity:
0.9991
SMILES:
C[C@H](N)C(=O)N1CC[C@@H](NS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)[C@H](C)C1
Target:
CCR

References

1. James E. Pease, et al. Chemokine Receptors in Allergy, Inflammation, and Infectious Disease. Top Med Chem (2015) 14: 1-40. 2. Lin Wang, et al. Antagonism of chemokine receptor CCR8 is ineffective in a primate model of asthma. Thorax 2013;68:506?512.