TargetMol

Praliciguat

Product Code:
 
TAR-T16569
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16569-1mg1mg£193.00
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TAR-T16569-2mg2mg£254.00
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TAR-T16569-5mg5mg£381.00
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TAR-T16569-1mL1 mL * 10 mM (in DMSO)£436.00
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TAR-T16569-10mg10mg£550.00
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TAR-T16569-25mg25mg£836.00
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TAR-T16569-50mg50mg£1,107.00
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TAR-T16569-100mg100mg£1,460.00
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Further Information

Bioactivity:
Praliciguat stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator. It also enhances NO signaling and acts as a vasodilator.
CAS:
1628730-49-3
Formula:
C21H14F8N6O2
Molecular Weight:
534.37
Pathway:
; GPCR/G Protein
Purity:
0.98
SMILES:
OC(CNc1nc(ncc1F)-c1cc(-c2ccon2)n(Cc2ccccc2F)n1)(C(F)(F)F)C(F)(F)F
Target:
Guanylate cyclase

References

1. Daniel P Zimmer, et al. Abstract 16938: IW-1973 is a Potent Soluble Guanylate Cyclase Stimulator in vitro and in vivo With Extensive Tissue Distribution.