TargetMol

Pranidipine

Product Code:
 
TAR-T16571
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16571-1mg1mg£98.00
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Quantity:
TAR-T16571-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T16571-5mg5mg£135.00
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TAR-T16571-10mg10mg£182.00
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TAR-T16571-25mg25mg£294.00
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Quantity:
TAR-T16571-50mg50mg£454.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Pranidipine is a novel, long-acting 1,4-dihydropyridine calcium channel blocker. It prolongs acetylcholine-induced relaxation in presence of endothelium as well as nitroglycerin-induced relaxation in absence of endothelium. It also has antihypertensive activity.
CAS:
99522-79-9
Formula:
C25H24N2O6
Molecular Weight:
448.475
Pathway:
Membrane transporter/Ion channel; Metabolism
Purity:
0.98
SMILES:
COC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OCC=Cc1ccccc1
Target:
Calcium Channel

References

1. Nakayama N, et al. Antihypertensive activity of OPC-13340, a new potent and long-acting dihydropyridine calcium antagonist, in rats. J Cardiovasc Pharmacol. 1990 May;15(5):836-44. 2. Toyoki Mori, Hiromichi Takase, et al. Pranidipine, a 1,4-Dihydropyridine Calcium Channel Blocker that Enhances Nitric Oxide-Induced Vascular Relaxation. Cardiovasc Drug Rev Spring 2001;19(1):1-8.