TargetMol

Pyrintegrin

Product Code:
 
TAR-T16695
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16695-1mg1mg£131.00
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TAR-T16695-2mg2mg£148.00
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TAR-T16695-5mg5mg£201.00
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TAR-T16695-1mL1 mL * 10 mM (in DMSO)£213.00
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TAR-T16695-10mg10mg£262.00
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TAR-T16695-25mg25mg£438.00
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TAR-T16695-50mg50mg£619.00
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TAR-T16695-100mg100mg£852.00
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This product comes from: United States.
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Further Information

Bioactivity:
Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signaling.
CAS:
1228445-38-2
Formula:
C23H25N5O3S
Molecular Weight:
451.55
Pathway:
Cytoskeletal Signaling
Purity:
0.9781
SMILES:
Oc1ccc2N(CCCc2c1)c1ccnc(Nc2ccc(cc2)S(=O)(=O)NCC2CC2)n1
Target:
Integrin

References

1. Shah BS, et al. Pyrintegrin Induces Soft Tissue Formation by Transplanted or Endogenous Cells. Sci Rep. 2017 Jan 27;7:36402. 2. Lee HW, et al. A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules. J Am Soc Nephrol. 2015 Nov;26(11):2741-52. 3. Xu Y, et al. Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8129-34.