TargetMol

RK-24466

Product Code:
 
TAR-T16760
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16760-1mg1mg£119.00
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TAR-T16760-5mg5mg£189.00
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TAR-T16760-1mL1 mL * 10 mM (in DMSO)£201.00
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TAR-T16760-10mg10mg£262.00
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TAR-T16760-25mg25mg£446.00
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TAR-T16760-50mg50mg£630.00
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Quantity:
TAR-T16760-100mg100mg£867.00
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This product comes from: United States.
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Further Information

Bioactivity:
RK-24466 is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.
CAS:
213743-31-8
Formula:
C23H22N4O
Molecular Weight:
370.456
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.9926
SMILES:
Nc1ncnc2n(cc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCC1
Target:
Src

References

1. Seo HH, et al. 7-cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d] pyrimidin-4-ylamine inhibits the proliferation and migration of vascular smooth muscle cells by suppressing ERK and Akt pathways. Eur J Pharmacol. 2017 Mar 5;798:35-42. 2. Arnold LD, et al. Pyrrolo[2,3-d]pyrimidines containing an extended 5-substituent as potent and selective inhibitors of lck I. Bioorg Med Chem Lett. 2000 Oct 2;10(19):2167-70.