TargetMol

Ilaprazole sodium

Product Code:
 
TAR-T1756
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1756-1mg1mg£95.00
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TAR-T1756-2mg2mg£106.00
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TAR-T1756-5mg5mg£127.00
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TAR-T1756-1mL1 mL * 10 mM (in DMSO)£128.00
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TAR-T1756-10mg10mg£145.00
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TAR-T1756-25mg25mg£230.00
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TAR-T1756-50mg50mg£329.00
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TAR-T1756-100mg100mg£490.00
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This product comes from: United States.
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Further Information

Bioactivity:
Ilaprazole, a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus of the gastric parietal cell where it is converted to an active sulfenamide form that binds to cysteine sulfhydryl groups on the luminal aspect of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production.
CAS:
172152-50-0
Formula:
C19H17N4NaO2S
Molecular Weight:
388.42
Pathway:
MAPK; Membrane transporter/Ion channel
Purity:
0.9955
SMILES:
[Na+].COc1ccnc(CS(=O)c2nc3ccc(cc3[n-]2)-n2cccc2)c1C
Target:
Proton pump; TOPK

References

1. Seo KA, et al. Xenobiotica. 2012 Mar;42(3):278-84.