TargetMol

Mc-MMAE

Product Code:
 
TAR-T18312
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T18312-1mg1mg£246.00
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TAR-T18312-5mg5mg£422.00
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TAR-T18312-10mg10mg£621.00
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TAR-T18312-1mL1 mL * 10 mM (in DMSO)£671.00
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TAR-T18312-25mg25mg£930.00
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TAR-T18312-50mg50mg£1,235.00
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Quantity:
TAR-T18312-100mg100mg£1,637.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Mc-MMAE is a drug-linker conjugate for ADC. Mc-MMAE is a maleimidocaproyl-conjugated monomethyl auristatin E, which is a potent tubulin inhibitor.
CAS:
863971-24-8
Formula:
C49H78N6O10
Molecular Weight:
911.195
Pathway:
Cytoskeletal Signaling
Purity:
0.98
SMILES:
CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)CCCCCN1C(=O)C=CC1=O)C(C)C
Target:
Microtubule Associated

References

1. Sanderson RJ, et al. In vivo drug-linker stability of an anti-CD30 dipeptide-linked auristatin immunoconjugate. Clin Cancer Res. 2005 Jan 15;11(2 Pt 1):843-52.