TargetMol

2S,4R-Sacubitril

Product Code:
 
TAR-T19113
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19113-10mg10mgEnquire
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TAR-T19113-50mg50mgEnquire
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TAR-T19113-1mg1mg£503.00
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TAR-T19113-5mg5mg£1,396.00
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This product comes from: United States.
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Further Information

Bioactivity:
2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is used in combination with valsartan for the treatment of patients with heart failure.
CAS:
T19113
Formula:
C25H31NO5
Molecular Weight:
425.52
Purity:
0.98
SMILES:
[H]N(C(CC(C)C(O)=O)=O)[C@H](CC(C=C1)=CC=C1C2=CC=CC=C2)C[C@@H](C)C(OCC)=O

References

1. Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44(4):554-9.