TargetMol

(2S,4S)-Sacubitril

Product Code:
 
TAR-T19114
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19114-1mg1mg£170.00
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TAR-T19114-5mg5mg£470.00
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TAR-T19114-10mg10mg£680.00
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TAR-T19114-25mg25mg£1,107.00
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TAR-T19114-50mg50mg£1,645.00
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Quantity:
TAR-T19114-100mg100mg£2,456.00
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This product comes from: United States.
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Further Information

Bioactivity:
(2S,4S)-Sacubitril is a stereoisomer derived from Sacubitril which is a potent NEP inhibitor.
CAS:
149709-63-7
Formula:
C24H28NO5 1/2Ca
Molecular Weight:
430.49
Purity:
0.9917
SMILES:
O=C([O-])CCC(N[C@@H](C[C@H](C)C(OCC)=O)CC1=CC=C(C2=CC=CC=C2)C=C1)=O.O=C([O-])CCC(N[C@@H](C[C@H](C)C(OCC)=O)CC3=CC=C(C4=CC=CC=C4)C=C3)=O.[Ca+2]

References

1. Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44(4):554-9. 2. Halama A, et, al. Synthesis, Isolation, and Analysis of Stereoisomers of Sacubitril. Org. Process Res. Dev. 2019, 23, 1, 102-107.