TargetMol

SGD-1882

Product Code:
 
TAR-T19560
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19560-1mg1mg£1,990.00
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This product comes from: United States.
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Further Information

Bioactivity:
SGD-1882 is a agent of cytotoxic, DNA minor-groove crosslinking pyrrolobenzodiazepine (PBD) dimer, and acting as the payload for ADCs.
CAS:
1222490-34-7
Formula:
C42H39N5O7
Molecular Weight:
725.802
Purity:
0.98
SMILES:
[H][C@@]12CC(=CN1C(=O)c1cc(OC)c(OCCCOc3cc4N=C[C@]5([H])CC(=CN5C(=O)c4cc3OC)c3ccc(OC)cc3)cc1N=C2)c1ccc(N)cc1

References

1. Eunhee G. Kim, et al. Strategies and Advancement in Antibody-Drug Conjugate Optimization for Targeted Cancer Therapeutics. Biomol Ther (Seoul). 2015 Nov; 23(6): 493-509. 2. Dowdy Jackson, et al. Using the Lessons Learned From the Clinic to Improve the Preclinical Development of Antibody Drug Conjugates. Pharm Res. 2015; 32(11): 3458-3469.