TargetMol

SM360320

Product Code:
 
TAR-T19675
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19675-1mg1mg£229.00
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TAR-T19675-5mg5mg£414.00
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TAR-T19675-1mL1 mL * 10 mM (in DMSO)£450.00
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TAR-T19675-10mg10mg£584.00
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TAR-T19675-25mg25mg£863.00
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TAR-T19675-50mg50mg£1,171.00
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TAR-T19675-100mg100mg£1,540.00
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TAR-T19675-500mg500mg£3,034.00
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Further Information

Bioactivity:
SM360320 is an effective and selective agonist of TLR7. SM360320 inhibits HCV replication in hepatocytes via a type I IFN-independent mechanism in addition to its IFN-mediated activity. SM360320 can be used for research on acting as an immunological adjuv
CAS:
226907-52-4
Formula:
C15H17N5O3
Molecular Weight:
315.333
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
COCCOc1nc(N)c2nc(O)n(Cc3ccccc3)c2n1
Target:
TLR

References

1. Hayashi T, et al. Treatment of autoimmune inflammation by a TLR7 ligand regulating the innate immune system. PLoS One. 2012;7(9):e45860. 2. Leroy V, et al. Sgp3 and TLR7 stimulation differentially alter the expression profile of modified polytropic retroviruses implicated in murine systemic lupus. J Autoimmun. 2012 Jun;38(4):361-8. 3. Russo C, et al. Small molecule Toll-like receptor 7 agonists localize to the MHC class II loading compartment of human plasmacytoid dendritic cells. Blood. 2011 May 26;117(21):5683-91. 4. Lee J, et al. Activation of anti-hepatitis C virus responses via Toll-like receptor 7. Proc Natl Acad Sci U S A. 2006;103(6):1828-1833.