TargetMol

4'-Hydroxy diclofenac

Product Code:
 
TAR-T19819
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T19819-10mg10mgEnquire
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TAR-T19819-1mg1mg£445.00
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Further Information

Bioactivity:
4'-Hydroxydiclofenac is a diclofenac metabolite.
CAS:
64118-84-9
Formula:
C14H11Cl2NO3
Molecular Weight:
312.15
Purity:
0.98
SMILES:
OC(=O)Cc1ccccc1Nc1c(Cl)cc(O)cc1Cl

References

1. Palyzov? A, Zahradn?k J, Mare?ov? H, Sokolov? L, Kysl?kov? E, Grulich M, ?t?p?nek V, ?ezanka T, Kysl?k P. Potential of the strain Raoultella sp. KDF8 for removal of analgesics. Folia Microbiol (Praha). 2017 Nov 11. doi: 10.1007/s12223-017-0563-2. [Epub ahead of print] PubMed PMID: 29127620. 2. Morgan AGM, Babu D, Michail K, Siraki AG. An evaluation of myeloperoxidase-mediated bio-activation of NSAIDs in promyelocytic leukemia (HL-60) cells for potential cytotoxic selectivity. Toxicol Lett. 2017 Oct 5;280:48-56. doi: 10.1016/j.toxlet.2017.07.894. Epub 2017 Jul 25. PubMed PMID: 28754375. 3. Po?r M, Boda G, Needs PW, Kroon PA, Lemli B, Bencsik T. Interaction of quercetin and its metabolites with warfarin: Displacement of warfarin from serum albumin and inhibition of CYP2C9 enzyme. Biomed Pharmacother. 2017 Apr;88:574-581. doi: 10.1016/j.biopha.2017.01.092. Epub 2017 Jan 27. PubMed PMID: 28135601. 4. Uraki M, Kawase A, Sayama H, Matsushima Y, Iwaki M. Effects of Adjuvant-Induced Inflammation on Disposition of Diclofenac and Its Metabolites in Perfused Rat Liver. J Pharm Sci. 2017 Apr;106(4):1175-1182. doi: 10.1016/j.xphs.2016.12.021. Epub 2017 Jan 3. PubMed PMID: 28062205.