TargetMol

J-147

Product Code:
 
TAR-T1993
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1993-1mg1mg£98.00
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TAR-T1993-5mg5mg£134.00
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TAR-T1993-1mL1 mL * 10 mM (in DMSO)£140.00
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TAR-T1993-10mg10mg£156.00
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TAR-T1993-25mg25mg£214.00
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TAR-T1993-50mg50mg£280.00
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TAR-T1993-100mg100mg£364.00
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TAR-T1993-500mg500mg£775.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
J147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate initially developed for the treatment of neurodegenerative conditions associated with aging that impacts many pathways implicated in the pathogenesis of diabetic neuropathy.
CAS:
1146963-51-0
Formula:
C18H17F3N2O2
Molecular Weight:
350.341
Pathway:
Neuroscience; GPCR/G Protein; Chromatin/Epigenetic
Purity:
0.9961
SMILES:
COc1cccc(C=NN(C(=O)C(F)(F)F)c2ccc(C)cc2C)c1
Target:
Epigenetic Reader Domain; Dopamine Receptor; Monoamine Oxidase

References

1. Lapchak PA, et al. J Neurol Neurophysiol. 2013 Aug;4(3). pii: 158.