TargetMol

4-Chloroloratadine

Product Code:
 
TAR-T20815
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T20815-1mg1mg£373.00
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Quantity:
TAR-T20815-100mg100mg£1,636.00
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This product comes from: United States.
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Further Information

Bioactivity:
4-Chloroloratadine is an impurity of Loratadine, a nonsedating-type histamine H1-receptor.
CAS:
165739-83-3
Formula:
C22H22Cl2N2O2
Molecular Weight:
417.33
Purity:
0.98
SMILES:
CCOC(=O)N1CCC(CC1)=C1c2ccc(Cl)cc2CCc2c(Cl)ccnc12

References

1. Abd el-HS, Colyer CL, Hassan WS, Shalaby A. Utility of 4-chloro-7-nitrobenzofurazan (NBD-CI) for the Spectrophotometric and spectrofluorometric determination of several antihistamine and antihypertensive drugs. J AOAC Int. 2013 Sep-Oct;96(5):968-75. PubMed PMID: 24282933. 2. Parkinson A, Clement RP, Casciano CN, Cayen MN. Evaluation of loratadine as an inducer of liver microsomal cytochrome P450 in rats and mice. Biochem Pharmacol. 1992 May 28;43(10):2169-80. PubMed PMID: 1534660. 3. Reddy KV, Babu JM, Kumar YR, Reddy SV, Kumar MK, Eswaraiah S, Reddy KR, Reddy MS, Bhaskar BV, Dubey PK, Vyas K. Impurity profile study of loratadine. J Pharm Biomed Anal. 2003 Apr 24;32(1):29-39. PubMed PMID: 12852446. 4. Zhong D, Blume H. [HPLC-determination of loratadine and its active metabolite descarboethoxyloratadine in human plasma]. Pharmazie. 1994 Oct;49(10):736-9. German. PubMed PMID: 7816900.