TargetMol

Pellitorine

Product Code:
 
TAR-T21165
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21165-1mg1mg£221.00
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TAR-T21165-5mg5mg£389.00
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TAR-T21165-10mg10mg£544.00
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TAR-T21165-25mg25mg£830.00
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TAR-T21165-50mg50mg£1,099.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Pellitorine is an extract of Tetradium daniellii, and acts as a TRPV1 antagonist.
CAS:
18836-52-7
Formula:
C14H25NO
Molecular Weight:
223.36
Pathway:
Membrane transporter/Ion channel
Purity:
0.9994
SMILES:
CCCCCC=CC=CC(=O)NCC(C)C
Target:
TRP/TRPV Channel

References

1. Rohm B, Riedel A, Ley JP, Widder S, Krammer GE, Somoza V. Capsaicin, nonivamide and trans-pellitorine decrease free fatty acid uptake without TRPV1 activation and increase acetyl-coenzyme A synthetase activity in Caco-2 cells. Food Funct. 2015 Jan;6(1):173-85. doi: 10.1039/c4fo00435c. Epub 2014 Nov 25. PubMed PMID: 25422952. 2. Veryser L, Taevernier L, Roche N, Peremans K, Burvenich C, De Spiegeleer B. Quantitative transdermal behavior of pellitorine from Anacyclus pyrethrum extract. Phytomedicine. 2014 Dec 15;21(14):1801-7. doi: 10.1016/j.phymed.2014.08.015. Epub 2014 Nov 11. PubMed PMID: 25481393. 3. Lee W, Ku SK, Min BW, Lee S, Jee JG, Kim JA, Bae JS. Vascular barrier protective effects of pellitorine in LPS-induced inflammation in vitro and in vivo. Fitoterapia. 2014 Jan;92:177-87. doi: 10.1016/j.fitote.2013.11.006. Epub 2013 Nov 18. PubMed PMID: 24262867. 4. Lieder B, Zaunschirm M, Holik AK, Ley JP, Hans J, Krammer GE, Somoza V. The Alkamide trans-Pellitorine Targets PPAR? via TRPV1 and TRPA1 to Reduce Lipid Accumulation in Developing 3T3-L1 Adipocytes. Front Pharmacol. 2017 May 31;8:316. doi: 10.3389/fphar.2017.00316. eCollection 2017. PubMed PMID: 28620299; PubMed Central PMCID: PMC5449966.