TargetMol

Maribavir

Product Code:
 
TAR-T2162
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2162-1mg1mg£99.00
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TAR-T2162-2mg2mg£111.00
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TAR-T2162-5mg5mg£142.00
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TAR-T2162-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T2162-10mg10mg£185.00
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TAR-T2162-25mg25mg£279.00
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TAR-T2162-50mg50mg£418.00
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TAR-T2162-100mg100mg£587.00
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This product comes from: United States.
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Further Information

Bioactivity:
Maribavir is an orally available benzimidazole riboside compound with activity against cytomegalovirus (CMV). Maribavir is a selective ATP competitor of the viral UL97 kinase, which is involved in viral nuclear maturation events, such as viral DNA assembly and movement of viral capsids from the nucleus of infected cells. Maribavir has activity against strains of CMV that are resistant to standard anti-CMV agents.
CAS:
176161-24-3
Formula:
C15H19Cl2N3O4
Molecular Weight:
376.24
Pathway:
Microbiology/Virology; Proteases/Proteasome;
Purity:
0.9985
SMILES:
CC(C)Nc1nc2cc(Cl)c(Cl)cc2n1[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O
Target:
HCV Protease

References

1. Shannon-Lowe CD, et al. The effects of Maribavir on the autophosphorylation of ganciclovir resistant mutants of the cytomegalovirus UL97 protein. Herpesviridae. 2010 Dec 7;1(1):4. 2. Biron KK, et al. Potent and selective inhibition of human cytomegalovirus replication by 1263W94, a benzimidazole L-riboside with a unique mode of action. Antimicrob Agents Chemother. 2002 Aug;46(8):2365-72.