TargetMol

AF 12198 Acetate

Product Code:
 
TAR-T21644L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-T21644L-1mg1mg£630.00
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TAR-T21644L-5mg5mg£1,332.00
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TAR-T21644L-10mg10mg£1,966.00
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TAR-T21644L-1mL1 mL * 10 mM (in DMSO)£3,195.00
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TAR-T21644L-25mg25mg£3,492.00
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TAR-T21644L-50mg50mg£5,203.00
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Quantity:
TAR-T21644L-100mg100mg£7,773.00
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Further Information

Bioactivity:
AF 12198 Acetate is a novel low molecular weight antagonist of IL-1
CAS:
T21644L
Formula:
C98H127N19O24
Molecular Weight:
1955.17
Pathway:
Immunology/Inflammation
Purity:
0.9527
SMILES:
CC(O)=O.CC(C)C[C@@H](C(N)=O)NC([C@H]1N(C([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC2=CC=C(O)C=C2)N(C([C@H](CCC(N)=O)NC([C@H](CC3=CC=C(O)C=C3)NC([C@H](CC4=CNC5=C4C=CC=C5)NC(CNC([C@H]6N(C([C@H]([C@H](O)C)NC([C@H](CC7=CNC8=C7C=CC=C8)NC([C@H](CCC(O)=O)NC([C@H](CC9=CC=CC=C9)NC(C)=O)=O)=O)=O)=O)CCC6)=O)=O)=O)=O)=O)C(C%10NCC%10)=O)=O)=O)=O)CCC1)=O
Target:
IL Receptor

References

1. Akeson A L , Woods C W , Hsieh L C , et al. AF12198, a Novel Low Molecular Weight Antagonist, Selectively Binds the Human Type I Interleukin (IL)-1 Receptor and Blocks in Vivo Responses to IL-1[J]. Journal of Biological Chemistry, 1996, 271(48):30517.