TargetMol

BRL 52537 hydrochloride

Product Code:
 
TAR-T21757
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21757-1mg1mg£139.00
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TAR-T21757-2mg2mg£165.00
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TAR-T21757-5mg5mg£209.00
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TAR-T21757-10mg10mg£269.00
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TAR-T21757-25mg25mg£439.00
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TAR-T21757-50mg50mg£611.00
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Quantity:
TAR-T21757-100mg100mg£840.00
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This product comes from: United States.
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Further Information

Bioactivity:
BRL 52537 hydrochloride is a selective and specific KOR agonist which has been implicated in neuroprotection from ischemic neuronal injury[1]. It is used for research into potential treatments for stroke and heart attack as well as more general brain research.
CAS:
112282-24-3
Formula:
C18H25Cl3N2O
Molecular Weight:
391.76
Pathway:
Endocrinology/Hormones; GPCR/G Protein; Neuroscience
Purity:
0.9904
SMILES:
O=C(Cc(cc1)cc(Cl)c1Cl)N1C(CN2CCCC2)CCCC1.Cl
Target:
Opioid Receptor

References

1. Zhang Z, et al. Kappa-opioid receptor selectivity for ischemic neuroprotection with BRL 52537 in rats. Anesth Analg. 2003 Dec;97(6):1776-1783. 2. Goyagi T, et al. Neuroprotective kappa-opioid receptor agonist BRL 52537 attenuates ischemia-evoked nitric oxide production in vivo in rats. Stroke. 2003 Jun;34(6):1533-8.