TargetMol

BD 1008 dihydrobromide

Product Code:
 
TAR-T21788
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21788-1mg1mg£217.00
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TAR-T21788-5mg5mg£324.00
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TAR-T21788-1mL1 mL * 10 mM (in DMSO)£362.00
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TAR-T21788-10mg10mg£466.00
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TAR-T21788-25mg25mg£648.00
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TAR-T21788-50mg50mg£830.00
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Quantity:
TAR-T21788-100mg100mg£1,203.00
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Further Information

Bioactivity:
BD1008 dihydrobromide is a selective antagonist of the sigma 1 (σ1) receptor (Ki = 2 nM). BD1008 dihydrobromide have high affinity for sigma1 receptors, moderate affinity for sigma2 receptors. BD1008 dihydrobromide attenuate the toxicity and stimulant effects of cocaine through antagonism of sigma receptors[1].
CAS:
138356-09-9
Formula:
C15H24Br2Cl2N2
Molecular Weight:
463.08
Pathway:
GPCR/G Protein
Purity:
0.9781
SMILES:
Br.Br.CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1
Target:
Sigma receptor

References

1. Matsumoto RR, et al. Novel analogs of the sigma receptor ligand BD1008 attenuate cocaine-induced toxicity in mice. Eur J Pharmacol. 2004 May 10;492(1):21-6.