TargetMol

TAE-1

Product Code:
 
TAR-T21825
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T21825-10mg10mg£102.00
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TAR-T21825-25mg25mg£142.00
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TAR-T21825-50mg50mg£195.00
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Quantity:
TAR-T21825-100mg100mg£254.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively.
CAS:
1414469-59-2
Formula:
C39H51I3N6O9
Molecular Weight:
1128.583
Pathway:
Neuroscience
Purity:
0.98
SMILES:
[I-].[I-].[I-].C[N+](C)(C)CCOC(=O)c1ccc(Oc2nc(Oc3ccc(cc3)C(=O)OCC[N+](C)(C)C)nc(Oc3ccc(cc3)C(=O)OCC[N+](C)(C)C)n2)cc1
Target:
Beta Amyloid; AChE

References

1. Biological activity of sym-triazines with acetylcholine-like substitutions as multitarget modulators of Alzheimer's disease.[J]. Acs Chemical Neuroscience, 2013, 4(6):924-9. 2. Veloso A J , Chow A M , Ganesh H , et al. Electrochemical Immunosensors for Effective Evaluation of Amyloid-Beta Modulators on Oligomeric and Fibrillar Aggregation Processes[J]. Analytical Chemistry, 2014, 86(10):4901-9.