TargetMol

TBCA

Product Code:
 
TAR-T21915
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21915-1mg1mg£112.00
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TAR-T21915-5mg5mg£155.00
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TAR-T21915-10mg10mg£189.00
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TAR-T21915-25mg25mg£264.00
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TAR-T21915-50mg50mg£356.00
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Further Information

Bioactivity:
TBCA is a highly selective CK2 (casein kinase II) inhibitor, IC50 = 110 nM, Ki = 77 nM. TBCA shows selectivity for CK2 over CK1, DYRK1A and a panel of 27 other kinases.
CAS:
934358-00-6
Formula:
C9H4Br4O2
Molecular Weight:
463.74
Pathway:
Stem Cells; Metabolism
Purity:
0.9931
SMILES:
C(=C/C(O)=O)C1=C(Br)C(Br)=C(Br)C(Br)=C1
Target:
Casein Kinase

References

1. Pagano MA, et al. Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors. Chembiochem. 2007;8(1):129-139. 2. Ryu SY, Kim S. Evaluation of CK2 inhibitor (E)-3-(2,3,4,5-tetrabromophenyl)acrylic acid (TBCA) in regulation of platelet function. Eur J Pharmacol. 2013;720(1-3):391-400.