TargetMol

EGFR/ErbB-2/ErbB-4 inhibitor-2

Product Code:
 
TAR-T21954
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21954-1mg1mg£177.00
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TAR-T21954-5mg5mg£303.00
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TAR-T21954-1mL1 mL * 10 mM (in DMSO)£340.00
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TAR-T21954-10mg10mg£434.00
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TAR-T21954-25mg25mg£671.00
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TAR-T21954-50mg50mg£914.00
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Quantity:
TAR-T21954-100mg100mg£1,211.00
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Quantity:
TAR-T21954-500mg500mg£2,344.00
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This product comes from: United States.
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Further Information

Bioactivity:
EGFR/ErbB2 Inhibitor is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively)
CAS:
179248-61-4
Formula:
C23H21N3O3
Molecular Weight:
387.439
Pathway:
JAK/STAT signaling; Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.981
SMILES:
COc1cc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2cc1OC
Target:
EGFR

References

1. Cockerill S , Stubberfield C , Stables J , et al. Indazolylamino quinazolines and pyridopyrimidines as inhibitors of the EGFr and C-erbB-2.[J]. Bioorganic & Medicinal Chemistry Letters, 2010, 32( 11):no-no.