TargetMol

Phthalazinone pyrazole

Product Code:
 
TAR-T21981
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21981-1mg1mg£164.00
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TAR-T21981-5mg5mg£301.00
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TAR-T21981-10mg10mg£470.00
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TAR-T21981-25mg25mg£707.00
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TAR-T21981-50mg50mg£978.00
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TAR-T21981-100mg100mg£1,291.00
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Quantity:
TAR-T21981-500mg500mg£2,456.00
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This product comes from: United States.
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Further Information

Bioactivity:
Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity.
CAS:
880487-62-7
Formula:
C18H15N5O
Molecular Weight:
317.352
Pathway:
Cell Cycle/Checkpoint; Chromatin/Epigenetic
Purity:
0.9822
SMILES:
Cc1cc(Nc2nn(-c3ccccc3)c(=O)c3ccccc23)n[nH]1
Target:
Aurora Kinase

References

1. Prime M E, Courtney S M, Brookfield F A, et al. Phthalazinone pyrazoles as potent, selective, and orally bioavailable inhibitors of Aurora-A kinase[J]. Journal of medicinal chemistry, 2010, 54(1): 312-319.